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It is supposed that these improvements of clinical symptoms are based on inhibition of vasoconstriction và platelet aggregation in pulmonary circulation.
Reduced invasion will leave the spiral arteries vasoreactive, & thus more likely khổng lồ undergo spontaneous transient vasoconstriction.
Activation of the extrinsic coagulation pathway causes additional adherence of platelets & even greater vasoconstriction.
Traditionally phenylephrine was reserved as a second-line drug for obstetrics because of concern about potential uteroplacental vasoconstriction.
Elevated high-density lipoprotein levels ameliorate abnormal vasoconstriction in early atherosclerosis.
When the core temperature falls, the hypothalamus increases core heat production and causes vasoconstriction which minimizes heat transfer khổng lồ the skin.
In particular, these studies showed that large doses of vasopressors caused vasoconstriction in the uteroplacental circulation which could result in fetal hypoxia.
First, ongoing perfusion of the placenta may cause continuous stimulation of production of vasoactive substances, which will tkết thúc khổng lồ increase placental vasoconstriction.

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Evidence from recent clinical trials suggests that concerns about uteroplacental vasoconstriction caused by phenylephrine are unfounded & this is the authors" drug of choice.
Nitric oxide alone, at least in this group of patients, does not unmask all the reversible vasoconstriction.
The vasoconstriction caused by ergometrine involves mainly capacitance vessels, leading to increase in central venous pressure và blood pressure.
This, however, results in generalized vasoconstriction, sludging of blood cells in the microcirculation, & poor perfusion of the tissues.
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